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DAR No 4. Roflumilast (Daxas®, Libertek®) in severe COPD

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Doubts on safety and questionable efficacy

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  • This drug is taken orally and is authorized in a small group of patients.
  • It has only been compared to placebo in patients who were not correctly treated.
  • There are doubts on its clinical efficacy in the trials.
  • There is concern regarding safety issues: suicide, weight loss, and absence of data on use over more than one year.
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