(go to content)

Logotipo navarra.es

Castellano | Euskara | Français | English

Use the search tool!

 Imagen decorativa
DTB: Vol 23, No 2

Content tools

Share it

  • Meneame
  • Delicious
  • Technorati
  • Google
  • Facebook
  • Yahoo

Facing ther unreliability of clinical trials literature 


Journal publications of randomised controlled trials (“literature”) have so far formed the basis for evidence of the effects of pharmaceuticals and biologics. In the last decade, progressively accumulating evidence has shown that literature is affected by reporting bias with evident implications for the reliability of any decision based on literature or its derivatives such as research synthesis. Instead of trying to reform the fields of research, industry, government, regulation and publishing, I propose basing public health decisions and reimbursement of any important intervention on independent trials and studies following the model pioneered by the Mario Negri Institute of Pharmacological Research.

 Author:

  • Tom Jefferson. Honorary Research Fellow. Centre for Evidence Based Medicine. Oxford OX2 6GG

- Link to the video "Facing the unreliability of clinical trials literature"

Enviar comentario

You can send us a comment or suggestion and we will respond to most frequently asked questions

Competing interests (complete this field only if you have competing interests)

 

 

 

 

Suggestions/Comments  

Government of Navarre

Contact us | Accessibility | Legal notice | Site map